Famine versus feast: understanding the metabolism of tumors in vivo

To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have sugge...

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Bibliographic Details
Main Authors: Vander Heiden, Matthew G., Mayers, Jared R.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105824
https://orcid.org/0000-0002-6702-4192
https://orcid.org/0000-0002-8607-1787