Famine versus feast: understanding the metabolism of tumors in vivo
To fuel unregulated proliferation, cancer cells alter metabolism to support macromolecule biosynthesis. Cell culture studies have revealed how different oncogenic mutations and nutrients impact metabolism. Glucose and glutamine are the primary fuels used in vitro; however, recent studies have sugge...
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Format: | Article |
Language: | en_US |
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Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/105824 https://orcid.org/0000-0002-6702-4192 https://orcid.org/0000-0002-8607-1787 |