Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes

The pluripotent state of embryonic stem cells (ESCs) is produced by active transcription of genes that control cell identity and repression of genes encoding lineage-specifying developmental regulators. Here, we use ESC cohesin ChIA-PET data to identify the local chromosomal structures at both activ...

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Bibliographic Details
Main Authors: Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Weintraub, Abraham S., Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Zhang, Lyndon Nuoxi, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105841
https://orcid.org/0000-0001-8225-6867
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/105841
https://orcid.org/0000-0001-8225-6867
https://orcid.org/0000-0001-8855-8647

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