Engineered bromodomains to explore the acetylproteome

Mass spectrometry-based analysis of the acetylproteome has highlighted a role for acetylation in a wide array of biological processes including gene regulation, metabolism, and cellular signaling. To date, anti-acetyllysine antibodies have been used as the predominant affinity reagent for enrichmen...

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Bibliographic Details
Main Authors: Del Rosario, Amanda M, Yaffe, Michael B, Gootenberg, Jonathan S, Bryson, Bryan D., White, Forest M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2016
Online Access:http://hdl.handle.net/1721.1/105868
https://orcid.org/0000-0002-9547-3251
https://orcid.org/0000-0002-1545-1651