Selective peptide inhibitors of antiapoptotic cellular and viral Bcl-2 proteins lead to cytochrome c release during latent Kaposi’s sarcoma-associated herpesvirus infection

Selective peptide inhibitors of antiapoptotic cellular and viral Bcl-2 proteins lead to cytochrome c release during latent Kaposi’s sarcoma-associated herpesvirus infection

Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with B-cell lymphomas including primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes latency within B cells by modulating or mimicking the antiapoptotic Bcl-2 family of proteins to promote cell survival. Our pre...

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Bibliographic Details
Main Authors: Burrer, Christine M., Chan, Gary C., Foight, Glenna W., Keating, Amy E.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/106146
https://orcid.org/0000-0003-3749-7092
https://orcid.org/0000-0003-4074-8980

Internet

http://hdl.handle.net/1721.1/106146
https://orcid.org/0000-0003-3749-7092
https://orcid.org/0000-0003-4074-8980

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