Selective peptide inhibitors of antiapoptotic cellular and viral Bcl-2 proteins lead to cytochrome c release during latent Kaposi’s sarcoma-associated herpesvirus infection
Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with B-cell lymphomas including primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes latency within B cells by modulating or mimicking the antiapoptotic Bcl-2 family of proteins to promote cell survival. Our pre...
Glavni autori: | Burrer, Christine M., Chan, Gary C., Foight, Glenna W., Keating, Amy E. |
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Daljnji autori: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Članak |
Jezik: | en_US |
Izdano: |
Elsevier
2016
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Online pristup: | http://hdl.handle.net/1721.1/106146 https://orcid.org/0000-0003-3749-7092 https://orcid.org/0000-0003-4074-8980 |
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