Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model

Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model

Intraperitoneal (IP) chemotherapy is more effective than systemic chemotherapy for treating advanced ovarian cancer, but is typically associated with severe complications due to high dose, frequent administration schedule, and use of non-biocompatible excipients/delivery vehicles. Here, we developed...

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Bibliographic Details
Main Authors: Wood, Joseph, Wang, Ying-Ying, Zeng, Qi, Simons, Brian W, Fu, Jie, Chuang, Chi-Mu, Lai, Samuel K, Wu, T.-C., Hung, Chien-Fu, Hanes, Justin, Simons, Brian W., Lai, Samuel K., Tang, Benjamin C., Yang, Ming, S.M. Massachusetts Institute of Technology, Yu, Tao, Ph. D. Massachusetts Institute of Technology
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer US 2016
Online Access:http://hdl.handle.net/1721.1/106169

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http://hdl.handle.net/1721.1/106169

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