Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
Methods to introduce targeted double-strand breaks (DSBs) into DNA enable precise genome editing by increasing the rate at which externally supplied DNA fragments are incorporated into the genome through homologous recombination. The efficiency of these methods is limited by nonhomologous end joinin...
主要な著者: | , , , , , |
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その他の著者: | |
フォーマット: | 論文 |
言語: | en_US |
出版事項: |
Nature Publishing Group
2017
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オンライン・アクセス: | http://hdl.handle.net/1721.1/106223 https://orcid.org/0000-0002-1090-6071 |