Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM

The orchestrated action of genes controls complex biological phenotypes, yet the systematic discovery of gene and drug combinations that modulate these phenotypes in human cells is labor intensive and challenging to scale. Here, we created a platform for the massively parallel screening of barcoded...

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Bibliographic Details
Main Authors: Wong, Siu Lun, Cui, Cheryl, Pregernig, Gabriela, Milani, Pamela, Choi, Gigi C. G., Adam, Miriam, Perli, Samuel D., Kazer, Samuel Weisgurt, Gaillard de Saint Germain, Alethe, Hermann, Mario, Shalek, Alexander K, Fraenkel, Ernest, Lu, Timothy K
Other Authors: Massachusetts Institute of Technology. Synthetic Biology Center
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/106350
https://orcid.org/0000-0001-5744-0873
https://orcid.org/0000-0002-0160-8742
https://orcid.org/0000-0001-7284-6337
https://orcid.org/0000-0003-0250-0474
https://orcid.org/0000-0002-8346-2184
https://orcid.org/0000-0002-7380-9594
https://orcid.org/0000-0001-9179-7972
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-9999-6690

Internet

http://hdl.handle.net/1721.1/106350
https://orcid.org/0000-0001-5744-0873
https://orcid.org/0000-0002-0160-8742
https://orcid.org/0000-0001-7284-6337
https://orcid.org/0000-0003-0250-0474
https://orcid.org/0000-0002-8346-2184
https://orcid.org/0000-0002-7380-9594
https://orcid.org/0000-0001-9179-7972
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-9999-6690

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