Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli

Recent advances in metabolic engineering have demonstrated the potential to exploit biological chemistry for the synthesis of complex molecules. Much of the progress to date has leveraged increasingly precise genetic tools to control the transcription and translation of enzymes for superior biosynth...

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Bibliographic Details
Main Authors: Biggs, Bradley Walters, Lim, Chin Giaw, Sagliani, Kristen, Shankar, Smriti, Stephanopoulos, Gregory, De Mey, Marjan, Ajikumar, Parayil Kumaran
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/106355
https://orcid.org/0000-0001-6909-4568