Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli
Recent advances in metabolic engineering have demonstrated the potential to exploit biological chemistry for the synthesis of complex molecules. Much of the progress to date has leveraged increasingly precise genetic tools to control the transcription and translation of enzymes for superior biosynth...
Main Authors: | Biggs, Bradley Walters, Lim, Chin Giaw, Sagliani, Kristen, Shankar, Smriti, Stephanopoulos, Gregory, De Mey, Marjan, Ajikumar, Parayil Kumaran |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2017
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Online Access: | http://hdl.handle.net/1721.1/106355 https://orcid.org/0000-0001-6909-4568 |
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