Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases
Since the discovery of NAD-dependent deacetylase activity of the silent information regulator-2 (SIR2) family (‘sirtuins’), many exciting connections between protein deacetylation and energy metabolism have been revealed. The importance of sirtuins in the regulation of many fundamental biological re...
Main Authors: | , |
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Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
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Online Access: | http://hdl.handle.net/1721.1/106460 https://orcid.org/0000-0003-4064-2510 |