Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers

Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers

Super-enhancers and stretch enhancers (SEs) drive expression of genes that play prominent roles in normal and disease cells, but the functional importance of these clustered enhancer elements is poorly understood, so it is not clear why genes key to cell identity have evolved regulation by such ele...

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Bibliographic Details
Main Authors: Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Weintraub, Abraham Selby, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/106469
https://orcid.org/0000-0003-0998-9882
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/106469
https://orcid.org/0000-0003-0998-9882
https://orcid.org/0000-0001-8855-8647

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