Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution

Patients with chromosome 13q deletion or normal cytogenetics represent the majority of chronic lymphocytic leukaemia (CLL) cases, yet have relatively few driver mutations. To better understand their genomic landscape, here we perform whole-genome sequencing on a cohort of patients enriched with thes...

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Main Authors: Kasar, S., Kim, J., Improgo, R., Tiao, G., Polak, P., Haradhvala, N., Lawrence, M. S., Kiezun, A., Fernandes, S. M., Bahl, S., Sougnez, C., Gabriel, S., Kim, H. T., Getz, G., Brown, J. R., Lander, Eric Steven
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: 文件
语言:en_US
出版: Nature Publishing Group 2017
在线阅读:http://hdl.handle.net/1721.1/106523