Enrichment of Extracellular Matrix Proteins from Tissues and Digestion into Peptides for Mass Spectrometry Analysis

The extracellular matrix (ECM) is a complex meshwork of cross-linked proteins that provides biophysical and biochemical cues that are major regulators of cell proliferation, survival, migration, etc. The ECM plays important roles in development and in diverse pathologies including cardio-vascular an...

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Bibliographic Details
Main Authors: Clauser, Karl R., Naba, Alexandra, Hynes, Richard O.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: MyJoVE Corporation 2017
Online Access:http://hdl.handle.net/1721.1/106549
https://orcid.org/0000-0001-7603-8396