Network Modeling Identifies Patient-specific Pathways in Glioblastoma

Glioblastoma is the most aggressive type of malignant human brain tumor. Molecular profiling experiments have revealed that these tumors are extremely heterogeneous. This heterogeneity is one of the principal challenges for developing targeted therapies. We hypothesize that despite the diverse molec...

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Bibliographic Details
Main Authors: Pokorny, Jenny L., Sio, Terence T., Iyekegbe, Dennis O., Sarkaria, Jann N., Tuncbag, Nurcan, Milani, Pamela, Johnson, Hannah, Dalin, Simona, Fraenkel, Ernest, White, Forest M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/106550
https://orcid.org/0000-0003-0250-0474
https://orcid.org/0000-0001-5024-9718
https://orcid.org/0000-0002-1545-1651
https://orcid.org/0000-0001-9249-8181