Sequencing the Mouse Y Chromosome Reveals Convergent Gene Acquisition and Amplification on Both Sex Chromosomes

We sequenced the MSY (male-specific region of the Y chromosome) of the C57BL/6J strain of the laboratory mouse Mus musculus. In contrast to theories that Y chromosomes are heterochromatic and gene poor, the mouse MSY is 99.9% euchromatic and contains about 700 protein-coding genes. Only 2% of the MS...

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Bibliographic Details
Main Authors: Pyntikova, Tatyana, Brown, Laura G., Graves, Tina, Minx, Patrick J., Fulton, Robert S., Kremitzki, Colin, Koutseva, Natalia, Mueller, Jacob L., Rozen, Steve, Hughes, Jennifer F., Owens, Elaine, Womack, James E., Murphy, William J., Cao, Qing, de Jong, Pieter, Warren, Wesley C., Wilson, Richard K., Skaletsky, Helen, Soh, Ying Qi Shirleen, Alfoldi, Jessica E., Page, David C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/106554
https://orcid.org/0000-0001-9920-3411