NAD+ and sirtuins in aging and disease

Nicotinamide adenine dinucleotide (NAD[superscript +]) is a classical coenzyme mediating many redox reactions. NAD[superscript +] also plays an important role in the regulation of NAD[superscript +]-consuming enzymes, including sirtuins, poly-ADP-ribose polymerases (PARPs), and CD38/157 ectoenzymes....

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Bibliographic Details
Main Authors: Imai, Shin-ichiro, Guarente, Leonard Pershing
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/106590
https://orcid.org/0000-0003-4064-2510