Reverse Electron Transfer Completes the Catalytic Cycle in a 2,3,5-Trifluorotyrosine-Substituted Ribonucleotide Reductase
Escherichia coli class Ia ribonucleotide reductase is composed of two subunits (α and β), which form an α2β2 complex that catalyzes the conversion of nucleoside 5′-diphosphates to deoxynucleotides (dNDPs). β2 contains the essential tyrosyl radical (Y[subscript 122][superscript •]) that generates a t...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society (ACS)
2017
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Online Access: | http://hdl.handle.net/1721.1/106601 https://orcid.org/0000-0001-5050-9719 https://orcid.org/0000-0002-8683-3593 https://orcid.org/0000-0001-8076-4489 |