Conservation and Covariance in Small Bacterial Phosphoglycosyltransferases Identify the Functional Catalytic Core

Phosphoglycosyltransferases (PGTs) catalyze the transfer of a C1′-phosphosugar from a soluble sugar nucleotide diphosphate to a polyprenol phosphate. These enzymes act at the membrane interface, forming the first membrane-associated intermediates in the biosynthesis of cell-surface glycans and glyco...

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Bibliographic Details
Main Authors: Luo, Lingqi, Kozakov, Dima, Vajda, Sandor, Allen, Karen N., Lukose, Vinita, Imperiali, Barbara
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/106626
https://orcid.org/0000-0003-3761-3743
https://orcid.org/0000-0002-5749-7869