Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes

Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes

Cells respond to stress by controlling gene expression at several levels, with little known about the role of translation. Here, we demonstrate a coordinated translational stress response system involving stress-specific reprogramming of tRNA wobble modifications that leads to selective translation...

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Bibliographic Details
Main Authors: Begley, Thomas J., Li, Fugen, Chan, Clement T. Y., Deng, Wenjun, DeMott, Michael S, Babu, I. Ramesh, Dedon, Peter C
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: American Chemical Society 2017
Online Access:http://hdl.handle.net/1721.1/106638
https://orcid.org/0000-0003-0011-3067

Internet

http://hdl.handle.net/1721.1/106638
https://orcid.org/0000-0003-0011-3067

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