Highly Predictive Reprogramming of tRNA Modifications Is Linked to Selective Expression of Codon-Biased Genes
Cells respond to stress by controlling gene expression at several levels, with little known about the role of translation. Here, we demonstrate a coordinated translational stress response system involving stress-specific reprogramming of tRNA wobble modifications that leads to selective translation...
Main Authors: | Begley, Thomas J., Li, Fugen, Chan, Clement T. Y., Deng, Wenjun, DeMott, Michael S, Babu, I. Ramesh, Dedon, Peter C |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society
2017
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Online Access: | http://hdl.handle.net/1721.1/106638 https://orcid.org/0000-0003-0011-3067 |
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