Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release

The SNARE-binding protein complexin (Cpx) has been demonstrated to regulate synaptic vesicle fusion. Previous studies are consistent with Cpx functioning either as a synaptic vesicle fusion clamp to prevent premature exocytosis, or as a facilitator to directly stimulate release. Here we examined con...

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Bibliografiska uppgifter
Huvudupphovsmän: Cho, Richard W., Song, Yun, Littleton, J. Troy
Övriga upphovsmän: Massachusetts Institute of Technology. Department of Biology
Materialtyp: Artikel
Språk:en_US
Publicerad: Elsevier B.V. 2017
Länkar:http://hdl.handle.net/1721.1/106802
https://orcid.org/0000-0001-5576-2887