Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, the role of inheritance is substantially greater. Previously, rare mutations in low-density lipoprotein (LDL) genes have been shown to contribute to MI risk...

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Bibliographic Details
Main Author: Lander, Eric Steven
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/106821