Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA

Pseudouridine is the most abundant RNA modification, yet except for a few well-studied cases, little is known about the modified positions and their function(s). Here, we develop Ψ-seq for transcriptome-wide quantitative mapping of pseudouridine. We validate Ψ-seq with spike-ins and de novo identifi...

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Bibliographic Details
Main Authors: Schwartz, Schraga, Bernstein, Douglas A., Mumbach, Maxwell R., Jovanovic, Marko, Herbst, Rebecca H., León-Ricardo, Brian X., Guttman, Mitchell, Satija, Rahul, Fink, Gerald, Engreitz, Jesse Michael, Lander, Eric Steven, Regev, Aviv
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/106822
https://orcid.org/0000-0002-5754-1719
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/106822
https://orcid.org/0000-0002-5754-1719
https://orcid.org/0000-0001-8567-2049

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