Modulating Mucin Hydration and Lubrication by Deglycosylation and Polyethylene Glycol Binding

Modulating Mucin Hydration and Lubrication by Deglycosylation and Polyethylene Glycol Binding

A key property of mucin glycoproteins is their exceptional capacity to hydrate and lubricate surfaces. In vivo, mucins assemble into mucus hydrogels that cover the epithelium and protect it from dehydration and shear stress. A better understanding of the origin of these properties could lead to new...

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Bibliographic Details
Main Authors: Boettcher, Kathrin, Geonnotti, Anthony R., Hirsch, Julie B., Lieleg, Oliver, Crouzier, Thomas, Kavanaugh, Nicole Lynn, Ribbeck, Katharina
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/106858
https://orcid.org/0000-0001-8260-338X

Internet

http://hdl.handle.net/1721.1/106858
https://orcid.org/0000-0001-8260-338X

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