Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
Thousands of human diseases could be treated by selectively controlling the expression of specific proteins in vivo. A new series of alkenyl amino alcohol (AAA) ionizable lipid nanoparticles (LNPs) capable of delivering human mRNA with unprecedented levels of in vivo efficacy is demonstrated. This s...
| Main Authors: | , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Wiley Blackwell
2017
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| Online Access: | http://hdl.handle.net/1721.1/106890 https://orcid.org/0000-0002-5585-9280 https://orcid.org/0000-0002-9436-2453 https://orcid.org/0000-0002-2301-7126 https://orcid.org/0000-0002-4917-7187 https://orcid.org/0000-0003-4255-0492 https://orcid.org/0000-0001-5629-4798 |