CXCL13 is a plasma biomarker of germinal center activity

Significantly higher levels of plasma CXCL13 [chemokine (C-X-C motif) ligand 13] were associated with the generation of broadly neutralizing antibodies (bnAbs) against HIV in a large longitudinal cohort of HIV-infected individuals. Germinal centers (GCs) perform the remarkable task of optimizing B-c...

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Bibliographic Details
Main Authors: Havenar-Daughton, Colin, Lindqvist, Madelene, Heit, Antje, Wu, Jennifer E., Reiss, Samantha M., Kendric, Kayla, Bélanger, Simon, Kasturi, Sudhir Pai, Landais, Elise, Akondy, Rama S., McGuire, Helen M., Bothwell, Marcella, Vagefi, Parsia A., Scully, Eileen, Tomaras, Georgia D., Davis, Mark M., Poignard, Pascal, Ahmed, Rafi, Walker, Bruce D., Pulendran, Bali, McElrath, M. Juliana, Kaufmann, Daniel E., Crotty, Shane
Other Authors: Ragon Institute of MGH, MIT and Harvard
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2017
Online Access:http://hdl.handle.net/1721.1/106932