Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in individuals with diabetes. Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically, but these approaches are limited by the adverse eff...

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Bibliographic Details
Main Authors: Gürtler, Mads, Millman, Jeffrey R, Pagliuca, Felicia W, McGarrigle, James J, Bochenek, Matthew A, Hollister-Lock, Jennifer, Oberholzer, Jose, Greiner, Dale L, Weir, Gordon C, Melton, Douglas A, Vegas, Arturo, Veiseh, Omid, Bader, Andrew, Doloff, Joshua C, Li, Jie, Chen, Michael, Olejnik, Karsten, Tam, Hok Hei, Jhunjhunwala, Siddharth, Langan, Erin, Aresta-Dasilva, Stephanie K, Gandham, Srujan Kumar, Langer, Robert S, Anderson, Daniel Griffith
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/106945
https://orcid.org/0000-0001-9522-8208
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https://orcid.org/0000-0003-1520-4180
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