High-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation
As key components of autocrine signaling, pericellular proteases, a disintegrin and metalloproteinases (ADAMs) in particular, are known to impact the microenvironment of individual cells and have significant implications in various pathological situations including cancer, inflammatory and vascular...
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Format: | Article |
Language: | en_US |
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Royal Society of Chemistry
2017
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Online Access: | http://hdl.handle.net/1721.1/106950 https://orcid.org/0000-0003-3150-6170 https://orcid.org/0000-0003-1224-8153 https://orcid.org/0000-0001-7215-1439 |