High-throughput functional comparison of promoter and enhancer activities

Promoters initiate RNA synthesis, and enhancers stimulate promoter activity. Whether promoter and enhancer activities are encoded distinctly in DNA sequences is unknown. We measured the enhancer and promoter activities of thousands of DNA fragments transduced into mouse neurons. We focused on genomi...

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Bibliográfalaš dieđut
Váldodahkkit: Nguyen, Thomas A., Jones, Richard D., Snavely, Andrew R., Pfenning, Andreas R., Kirchner, Rory, Hemberg, Martin, Gray, Jesse M.
Eará dahkkit: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Materiálatiipa: Artihkal
Giella:en_US
Almmustuhtton: Cold Spring Harbor Laboratory Press 2017
Liŋkkat:http://hdl.handle.net/1721.1/106954
https://orcid.org/0000-0002-3447-9801