The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

Adult stem cells must limit their rate of protein synthesis, but the underlying mechanisms remain largely unexplored. Differences in protein synthesis among hematopoietic stem cells (HSCs) and progenitor cells did not correlate with differences in proteasome activity, total RNA content, mRNA content...

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Bibliographic Details
Main Authors: Signer, Robert A.J., Qi, Le, Zhao, Zhiyu, Thompson, David, Sigova, Alla A., Fan, Zi Peng, DeMartino, George N., Sonenberg, Nahum, Morrison, Sean J., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2017
Online Access:http://hdl.handle.net/1721.1/106975
https://orcid.org/0000-0001-8855-8647