A Multi-RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs

Packaging multiple small interfering RNA (siRNA) molecules into nanostructures at precisely defined ratios is a powerful delivery strategy for effective RNA interference (RNAi) therapy. We present a novel RNA nanotechnology based approach to produce multiple components of polymerized siRNA molecules...

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Bibliographic Details
Main Authors: Park, Jae Hyon, Roh, Young Hoon, Dreaden, Erik, Yun, Dong Soo, Shopsowitz, Kevin, Hammond, Paula T, Deng, Zhou J.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/106977
https://orcid.org/0000-0002-4954-8443
https://orcid.org/0000-0003-3988-0837