Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery

Synthetic regulatory circuits encoded in RNA rather than DNA could provide a means to control cell behavior while avoiding potentially harmful genomic integration in therapeutic applications. We create post-transcriptional circuits using RNA-binding proteins, which can be wired in a plug-and-play fa...

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Bibliographic Details
Main Authors: Endo, Kei, Saito, Hirohide, Wroblewska, Liliana, Kitada, Tasuku, Siciliano, Velia, DiAndreth, Breanna Elizabeth, Weiss, Ron
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/107113
https://orcid.org/0000-0003-2265-3363
https://orcid.org/0000-0001-7734-9153
https://orcid.org/0000-0002-0302-6834
https://orcid.org/0000-0003-0396-2443

Internet

http://hdl.handle.net/1721.1/107113
https://orcid.org/0000-0003-2265-3363
https://orcid.org/0000-0001-7734-9153
https://orcid.org/0000-0002-0302-6834
https://orcid.org/0000-0003-0396-2443

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