3D Chromosome Regulatory Landscape of Human Pluripotent Cells

In this study, we describe the 3D chromosome regulatory landscape of human naive and primed embryonic stem cells. To devise this map, we identified transcriptional enhancers and insulators in these cells and placed them within the context of cohesin-associated CTCF-CTCF loops using cohesin ChIA-PET...

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Bibliographic Details
Main Authors: Ji, Xiong, Powell, Benjamin E., Shachar, Sigal, Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Dadon, Daniel Benjamin, Fan, Zi Peng, Borges-Rivera, Diego Ramon, Weintraub, Abraham Selby, Jaenisch, Rudolf, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/107115
https://orcid.org/0000-0002-7256-3158
https://orcid.org/0000-0002-1650-2289
https://orcid.org/0000-0003-0998-9882
https://orcid.org/0000-0001-8855-8647