3D Chromosome Regulatory Landscape of Human Pluripotent Cells
In this study, we describe the 3D chromosome regulatory landscape of human naive and primed embryonic stem cells. To devise this map, we identified transcriptional enhancers and insulators in these cells and placed them within the context of cohesin-associated CTCF-CTCF loops using cohesin ChIA-PET...
Main Authors: | Ji, Xiong, Powell, Benjamin E., Shachar, Sigal, Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Dadon, Daniel Benjamin, Fan, Zi Peng, Borges-Rivera, Diego Ramon, Weintraub, Abraham Selby, Jaenisch, Rudolf, Young, Richard A. |
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Other Authors: | Massachusetts Institute of Technology. Computational and Systems Biology Program |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
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Online Access: | http://hdl.handle.net/1721.1/107115 https://orcid.org/0000-0002-7256-3158 https://orcid.org/0000-0002-1650-2289 https://orcid.org/0000-0003-0998-9882 https://orcid.org/0000-0001-8855-8647 |
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