Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

Motor units are the fundamental elements responsible for muscle movement. They are formed by lower motor neurons and their muscle targets, synapsed via neuromuscular junctions (NMJs). The loss of NMJs in neurodegenerative disorders (such as amyotrophic lateral sclerosis or spinal muscle atrophy) or...

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Bibliographic Details
Main Authors: Platt, Randall Jeffrey, Subramanian, Vidya, Pearl, Taylor M., Rowlands, Christopher, Chan, Vincent, Boyer, Laurie Ann, So, Peter T. C., Kamm, Roger Dale, Uzel, Sebastien Guy Marcel
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2017
Online Access:http://hdl.handle.net/1721.1/107135
https://orcid.org/0000-0002-8261-2371
https://orcid.org/0000-0003-3491-4962
https://orcid.org/0000-0003-4698-6488
https://orcid.org/0000-0002-7232-304X