A synergistic DNA logic predicts genome-wide chromatin accessibility

A synergistic DNA logic predicts genome-wide chromatin accessibility

Enhancers and promoters commonly occur in accessible chromatin characterized by depleted nucleosome contact; however, it is unclear how chromatin accessibility is governed. We show that log-additive cis-acting DNA sequence features can predict chromatin accessibility at high spatial resolution. We d...

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Bibliographic Details
Main Authors: Sherwood, Richard I., Emons, Bart J.M., Hashimoto, Tatsunori Benjamin, Kang, Daniel D., Rajagopal, Nisha, Barkal, Amira, Zeng, Haoyang, Srinivasan, Sharanya, Jaakkola, Tommi S., Gifford, David K.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2017
Online Access:http://hdl.handle.net/1721.1/107146
https://orcid.org/0000-0003-0521-5855
https://orcid.org/0000-0001-5809-3041
https://orcid.org/0000-0003-1057-2865
https://orcid.org/0000-0002-2199-0379
https://orcid.org/0000-0003-1709-4034

Internet

http://hdl.handle.net/1721.1/107146
https://orcid.org/0000-0003-0521-5855
https://orcid.org/0000-0001-5809-3041
https://orcid.org/0000-0003-1057-2865
https://orcid.org/0000-0002-2199-0379
https://orcid.org/0000-0003-1709-4034

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