A PK–PD model of ketamine-induced high-frequency oscillations

Objective. Ketamine is a widely used drug with clinical and research applications, and also known to be used as a recreational drug. Ketamine produces conspicuous changes in the electrocorticographic (ECoG) signals observed both in humans and rodents. In rodents, the intracranial ECoG displays a hig...

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Bibliographic Details
Main Authors: Hartnack, Katharine, Fath, Amanda B, Flores Plaza, Francisco Javier, Ching, Shinung, Brown, Emery Neal, Purdon, Patrick Lee, Wilson, Matthew A.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: IOP Publishing 2017
Online Access:http://hdl.handle.net/1721.1/107204
https://orcid.org/0000-0002-8974-9717
https://orcid.org/0000-0001-5651-5060
https://orcid.org/0000-0001-7149-3584
https://orcid.org/0000-0003-2668-7819