Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins

Effective delivery of therapeutic proteins is a formidable challenge. Herein, using a unique polymer family with a wide-ranging set of cationic and hydrophobic features, we developed a novel nanoparticle (NP) platform capable of installing protein ligands on the particle surface and simultaneously c...

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Bibliographic Details
Main Authors: Zhu, Xi, Wu, Jun, Shan, Wei, Tao, Wei, Zhao, Lili, Lim, Jong-Min, D'Ortenzio, Mathew, Karnik, Rohit, Huang, Yuan, Shi, Jinjun, Farokhzad, Omid C.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/107246
https://orcid.org/0000-0003-0588-9286