Programming a Human Commensal Bacterium, Bacteroides thetaiotaomicron, to Sense and Respond to Stimuli in the Murine Gut Microbiota

Engineering commensal organisms for challenging applications, such as modulating the gut ecosystem, is hampered by the lack of genetic parts. Here, we describe promoters, ribosome-binding sites, and inducible systems for use in the commensal bacterium Bacteroides thetaiotaomicron, a prevalent and st...

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Bibliographic Details
Main Authors: Tucker, Alex C., Voigt, Christopher A., Lu, Timothy K, Mimee, Mark Kyle
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/107264
https://orcid.org/0000-0002-3083-2671
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0002-9999-6690