m[superscript 6]A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

N6-methyl-adenosine (m[superscript 6]A) is the most abundant modification on messenger RNAs and is linked to human diseases, but its functions in mammalian development are poorly understood. Here we reveal the evolutionary conservation and function of m[superscript 6]A by mapping the m[superscript 6...

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Bibliographic Details
Main Authors: Batista, Pedro J., Molinie, Benoit, Wang, Jinkai, Qu, Kun, Zhang, Jiajing, Li, Lingjie, Bouley, Donna M., Lujan, Ernesto, Haddad, Bahareh, Daneshvar, Kaveh, Carter, Ava C., Flynn, Ryan A., Zhou, Chan, Wernig, Marius, Mullen, Alan C., Xing, Yi, Giallourakis, Cosmas C., Chang, Howard Y., Lim, Kok Seong, Dedon, Peter C
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/107417
https://orcid.org/0000-0003-0011-3067