Untying Knotted DNA with Elongational Flows

We present Brownian dynamics simulations of initially knotted double-stranded DNA molecules untying in elongational flows. We show that the motions of the knots are governed by a diffusion–convection equation by deriving scalings that collapse the simulation data. When being convected, all knots dis...

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Bibliographic Details
Main Authors: Renner, Christopher Benjamin, Doyle, Patrick S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2017
Online Access:http://hdl.handle.net/1721.1/107433
https://orcid.org/0000-0003-1687-4522