Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines
To maintain protein homeostasis, AAA+ proteolytic machines degrade damaged and unneeded proteins in bacteria, archaea and eukaryotes. This process involves the ATP-dependent unfolding of a target protein and its subsequent translocation into a self-compartmentalized proteolytic chamber. Related AAA+...
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Format: | Article |
Language: | en_US |
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Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/107469 https://orcid.org/0000-0002-1719-5399 |