Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines

To maintain protein homeostasis, AAA+ proteolytic machines degrade damaged and unneeded proteins in bacteria, archaea and eukaryotes. This process involves the ATP-dependent unfolding of a target protein and its subsequent translocation into a self-compartmentalized proteolytic chamber. Related AAA+...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Olivares, Adrian O., Baker, Tania, Sauer, Robert T.
Rannpháirtithe: Massachusetts Institute of Technology. Department of Biology
Formáid: Alt
Teanga:en_US
Foilsithe / Cruthaithe: Nature Publishing Group 2017
Rochtain ar líne:http://hdl.handle.net/1721.1/107469
https://orcid.org/0000-0002-1719-5399