Subnuclear foci quantification using high-throughput 3D image cytometry

Subnuclear foci quantification using high-throughput 3D image cytometry

Ionising radiation causes various types of DNA damages including double strand breaks (DSBs). DSBs are often recognized by DNA repair protein ATM which forms gamma-H2AX foci at the site of the DSBs that can be visualized using immunohistochemistry. However most of such experiments are of low through...

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Bibliographic Details
Main Authors: Wadduwage, Dushan N., Matsudaira, Paul, So, Peter T. C., Parrish, Marcus Curtis, Choi, Heejin, Engelward, Bevin P
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: SPIE 2017
Online Access:http://hdl.handle.net/1721.1/107492
https://orcid.org/0000-0002-5472-3621
https://orcid.org/0000-0003-3681-7410

Internet

http://hdl.handle.net/1721.1/107492
https://orcid.org/0000-0002-5472-3621
https://orcid.org/0000-0003-3681-7410

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