CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that exhibits extremely high levels of genetic complexity and yet a relatively uniform transcriptional program. We postulate that TNBC might be highly dependent on uninterrupted transcription of a key set of genes with...

Full description

Bibliographic Details
Main Authors: Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Gray, Nathanael S., Zhao, Jean J., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier B.V. 2017
Online Access:http://hdl.handle.net/1721.1/107736
https://orcid.org/0000-0001-8855-8647

Internet

http://hdl.handle.net/1721.1/107736
https://orcid.org/0000-0001-8855-8647

Similar Items