Local microRNA delivery targets Palladin and prevents metastatic breast cancer

Metastasis is the primary cause for mortality in breast cancer. MicroRNAs, gene expression master regulators, constitute an attractive candidate to control metastasis. Here we show that breast cancer metastasis can be prevented by miR-96 or miR-182 treatment, and decipher the mechanism of action. We...

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Bibliographic Details
Main Authors: Gilam, Avital, Weissglas-Volkov, Daphna, Friedman, Eitan, Shomron, Noam, Osorio De Castro Conde, Joao, Artzi, Natalie, Oliva, Nuria
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/107761
https://orcid.org/0000-0001-8422-6792
https://orcid.org/0000-0003-3055-797X