PLGA nanoparticle encapsulation reduces toxicity while retaining the therapeutic efficacy of EtNBS-PDT in vitro

Photodynamic therapy regimens, which use light-activated molecules known as photosensitizers, are highly selective against many malignancies and can bypass certain challenging therapeutic resistance mechanisms. Photosensitizers such as the small cationic molecule EtNBS (5-ethylamino-9-diethyl-aminob...

Full description

Bibliographic Details
Main Authors: Hung, Hsin-I, Klein, Oliver J., Peterson, Sam W., Rokosh, Sarah R., Osseiran, Sam, Nowell, Nicholas H., Evans, Conor L.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/107778
https://orcid.org/0000-0002-6693-3714