Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform

Biochemical gradients are ubiquitous in biology. At the tissue level, they dictate differentiation patterning or cell migration. Recapitulating in vitro the complexity of such concentration profiles with great spatial and dynamic control is crucial in order to understand the underlying mechanisms of...

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Bibliographic Details
Main Authors: Uzel, Sebastien GM, Amadi, Ovid C, Pearl, Taylor M., Lee, Richard T, So, Peter T. C., Kamm, Roger Dale
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Wiley Blackwell 2017
Online Access:http://hdl.handle.net/1721.1/107828
https://orcid.org/0000-0003-4698-6488
https://orcid.org/0000-0002-7232-304X