Single-Cell Migration in Complex Microenvironments: Mechanics and Signaling Dynamics

Cells are highly dynamic and mechanical automata powered by molecular motors that respond to external cues. Intracellular signaling pathways, either chemical or mechanical, can be activated and spatially coordinated to induce polarized cell states and directional migration. Physiologically, cells na...

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Bibliographic Details
Main Authors: Mak, Michael, Spill, Fabian, Kamm, Roger Dale, Zaman, Muhammad
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: ASME International 2017
Online Access:http://hdl.handle.net/1721.1/107833
https://orcid.org/0000-0002-6719-9929
https://orcid.org/0000-0001-8462-5080
https://orcid.org/0000-0002-7232-304X